產(chǎn)品屬性：
產(chǎn)品名稱 | VBIT-4 |
規(guī)格 | 5mg、10mg、50mg、100mg |
貨號 | EY-01Y12385 |
Cas No.: 2086257-77-2
別名: N/A
化學名: N/A
分子式: C21H23ClF3N3O3
分子量: 457.87
溶解度: DMSO: 125 mg/mL (273.00 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
VBIT-4 is an inhibitor of voltage-dependent anion channel 1 (VDAC1) oligomerization with a binding affinity (Kd) of 17 μM. VBIT-4, as an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders, such as neurodegenerative and cardiovascular diseases[1].
[1]. Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003.
特別提醒公司產(chǎn)品僅供科研使用
