產(chǎn)品屬性：
產(chǎn)品名稱 | c-Kit-IN-2 |
規(guī)格 | 100mg、250mg、500mg |
貨號 | EY-01Y12911 |
Cas No.: 2121515-37-3
別名: N/A
化學名: N/A
分子式: C25H29N9O2S
分子量: 519.62
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
c-Kit-IN-2 is a c-KIT inhibitor with an IC50 of 82 nM, shows superior antiproliferative activities against all the three GIST cell lines, GIST882, GIST430, and GIST48, with GI50s of 3, 1, and 2 nM, respectively[1].IC50: 82 nM (c-KIT)[1][1]. Wu TS, et al. Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants. J Med Chem. 2019 Apr 25;62(8):3940-3957.
特別提醒公司產(chǎn)品僅供科研使用
