產(chǎn)品屬性：
產(chǎn)品名稱 | SR 7826 |
規(guī)格 | 10 mg、50 mg |
貨號 | EY-01Y13047 |
Cas No.: 1219728-20-7
別名: N/A
化學名: N/A
分子式: C22H21N5O2
分子量: 387.43
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Potent and selective LIMK inhibitor (IC50 values are 43, 5536 and 6565 nM for LIMK1, ROCKI and ROCKII, respectively). Inhibits cofilin phosphorylation in A7r5 cells and suppresses migration and invasion of PC-3 cells in vitro. Orally bioavailable.Yin et al (2015) Bis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors. J.Med.Chem. 58 1846 PMID:25621531
特別提醒公司產(chǎn)品僅供科研使用
