產(chǎn)品屬性：
產(chǎn)品名稱 | U-51605 |
規(guī)格 | 100μg、500μg、1mg、5mg |
貨號 | EY-01Y13228 |
Cas No.: 64192-56-9
別名: N/A
化學名: N/A
分子式: C20H32N2O2
分子量: 332.5
溶解度: DMF: >100 mg/ml (from U-46619),DMSO: >100 mg/ml (from U-46619),Ethanol: >100 mg/ml (from U-46619),PBS pH 7.2: >2 mg/ml (from U-46619)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
U-51605 is a stable analog of the endoperoxide prostaglandin H2 (PGH2). It is an inhibitor of both prostacyclin (PGI) and thromboxane (TX) synthases with more selectivity towards PGI synthase. U-51605 is also a partial agonist at TP receptors. In human foreskin fibroblasts, U-51605 inhibits PGI synthase at a concentration of 2.8 μM, whereas, human platelet TX synthase is inhibited at a concentration of 5.6 μM. At concentrations up to 1 μM, U-51605 reduced the release of prostacyclin in SHR aorta elicited by the calcium ionophore A-23187 with no effect on TXA2 production and yet significantly increased PGE2 and PGF2α release.
特別提醒公司產(chǎn)品僅供科研使用
