產(chǎn)品屬性：
產(chǎn)品名稱 | Prostaglandin D2 Ethanolamide |
規(guī)格 | 500μg、1mg、5mg |
貨號 | EY-01Y13639 |
Cas No.: 398138-28-8
別名: N/A
化學(xué)名: N/A
分子式: C22H37NO5
分子量: 395.5
溶解度: DMF: 8.3 mg/ml,DMSO: 8.3 mg/ml,Ethanol: 12.5 mg/ml,PBS (7.2): 2.5 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase. PGD2-EA is inactive against recombinant prostanoid receptors, including the D prostanoid receptor. It increases the frequency of miniature inhibitory postsynaptic currents in primary cultured hippocampal neurons, an effect which is the opposite of that induced by anandamide.. PGD2-EA also induces apoptosis in colorectal carcinoma cell lines.
特別提醒公司產(chǎn)品僅供科研使用
