產(chǎn)品屬性：
產(chǎn)品名稱 | iRucaparib-AP6 |
規(guī)格 | 1mg、5mg、10mg |
貨號 | EY-01Y13743 |
Cas No.: 2410557-00-3
別名: N/A
化學(xué)名: N/A
分子式: C46H55FN6O11
分子量: 886.96
溶解度: DMSO: 50 mg/mL (56.37 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using thePROTAC approach. iRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1[1].[1]. Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation.Nat Chem Biol. 2019 Dec;15(12):1223-1231.
特別提醒公司產(chǎn)品僅供科研使用
