產品屬性：
產品名稱 | Umbralisib R-enantiomer |
規(guī)格 | 2mg、5mg、10mg、50mg |
貨號 | EY-01Y15543 |
Cas No.: 1532533-69-9
別名: N/A
化學名: N/A
分子式: C31H24F3N5O3
分子量: 571.55
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Umbralisib R-enantiomer (TGR-1202 R-enantiomer) is a PI3Kδ inhibitor, which is the less active enantiomer of TGR-1202.
PI3Kδ
Umbralisib R-enantiomer (TGR-1202 R-enantiomer) (Formula A) exhibits a 50% inhibitory concentration (IC50) with respect to the δ type PI3-kinase that is at least 20-fold lower than the inhibitor's IC50 with respect to the rest of the other PI3K isoforms (i.e., a, β, and γ)[1].[1]. Michael Weiss, et al. Combination of anti-cd20 antibody and pi3 kinase selective inhibitor. WO2014071125A1.
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