產品屬性：
產品名稱 | SB 4 |
規(guī)格 | 50 mg |
貨號 | EY-01Y16747 |
Cas No.: 100874-08-6
別名: N/A
化學名: N/A
分子式: C14H10BrNOS
分子量: 320.2
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Potent BMP4 agonist (EC50 = 74 nM). Activates canonical BMP signaling and increases SMAD-1/5/9 phosphorylation, with no effect on p-SMAD-2, p-SMAD-3 or p-TAK1. Bypasses noggin-induced inhibition of type I BMP receptors.Bradford et al (2019) High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds. J.Biol.Chem. 294 3125 PMID:30602563
特別提醒公司產品僅供科研使用
