產(chǎn)品屬性：
產(chǎn)品名稱 | Pirepemat |
規(guī)格 | 5 mg、10 mg、25 mg、50 mg |
貨號 | EY-01Y18099 |
Cas No.: 1227638-29-0
別名: N/A
化學(xué)名: N/A
分子式: C11H13F2NO
分子量: 213.22
溶解度: DMSO : 100 mg/mL (469.00 mM; Need ultrasonic)
儲存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson’s disease[1][2].IRL752 displayed its highest in vitro affinities for 5-HT and NA-related targets[2].IRL752 (3.7-100 μmol/kg, s.c.) has no significant effect on acute hyper-dopaminergic or hypo-glutamatergic motor responses, but reversed deficits resulting from hypomonoaminergic function[2].[1]. Ipsen and IRLAB Enter Exclusive Worldwide Licensing Agreement Aimed to Improve the Lives of People Living with Parkinson’s Disease. [2]. S Hjorth, et al. (3 S)-3-(2,3-difluorophenyl)-3-methoxypyrrolidine (IRL752) -a Novel Cortical-Preferring Catecholamine Transmission- and Cognition-Promoting Agent. J Pharmacol Exp Ther. 2020 Sep;374(3):404-419.
特別提醒公司產(chǎn)品僅供科研使用
