產品屬性：
產品名稱 | Spirohexenolide A |
規(guī)格 | 100μg、500μg |
貨號 | EY-01Y19554 |
Cas No.: 1193347-22-6
別名: N/A
化學名: N/A
分子式: C25H28O5
分子量: 408.5
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Spirohexenolide A is a metabolite originally isolated from S. platensis. It inhibits growth in the NCI-60 cancer cell line panel (GI50s = 0.1-17 μM) with the RPMI-8226 multiple myeloma, HOP-92 lung, and SW620 colon cancer cell lines being most sensitive (GI50s = 254, 191, and 565 nM, respectively). Spirohexenolide A also binds to human macrophage migration inhibition factor (MIF; Kd = 35.9 μM) and inhibits MIF cellular uptake and lysosomal localization in HCT116 cells.
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